If you are interested in joining our team, please see our current openings. If you do not see a position that matches your skills and interests, send your resume to and let us know why you would be a good fit for the Principia team.

Our Culture

In 2011, we set out to make a superior class of medicines to address unmet medical needs. We knew back then that we first had to create a place that was designed to foster that mission, a place where incredibly talented individuals are empowered to do their best work through excellence in science, development and strategy.
Our guiding principles are:

• Empowerment
• Accountability
• Speed
• Focus
• Scientific Excellence
• Teamwork
• Respect

As Principia continues to grow, we hope that these principles will serve each new person joining our ranks.


Current Openings

Senior Scientist/ Associate Director, Medicinal Chemistry



Our goal is to offer attractive benefits to our employees and remain competitive in our industry.

• Competitive salary and bonus plan
• Comprehensive and competitive benefit coverage
• Ample paid time off + paid holidays
• Flexible work options
• Regular happy hours 
• Stocked snack pantry + weekly breakfast